Topic: Bacterial and Viral Infections – Silver Iontophoresis Treatment
How does the treatment work?
Bacterial and Viral Infections – Silver Iontophoresis Treatment. Silver iontophoresis is an electromedical treatment for surface and internal body infections, and surface wound and ulcer healing.
Silver iontophoresis uses an electric voltage, just as is generated by a battery, to move atoms of silver with a positive electric charge (called ‘cations’), through living tissue.
The treatment is delivered via two silver electro-plated cloth electrodes (pads), positioned on the body. Depending on how the pads are positioned, the treatment can target an infection inside the body, or of the skin.
Silver iontophoresis is also effective for antibiotic resistant superbug bacterial infections, and for viral infections.
This is a targeted treatment that is sub-sensory (no pain), and has no drug side effects.
Bacterial and Viral Infections – Silver Iontophoresis Treatment
What infections can be treated?
Silver iontophoresis can be targeted at virtually any localized bacterial or viral infection including and not limited to:
- Ear, nose and throat (ENT) infections including sinus infections
- Gum infections (gingivitis)
- Chest (upper and lower respiratory tract) infections: Bronchitis, Pneumonia
- Stomach infections such as Helicobacter pylori
- Liver infections (viral hepatitis)
- Herpes viruses infections
- Pancreatic infections
- Spleen infections
- Reproductive organ infections (male & female) including ovarian, uterine and cervical infections: HPV
- Bladder and Kidney infections (upper and lower UTI)
- Bone, joint and muscle infections (Osteomyelitis, Septic Arthritis, Pyomyositis).
- Antibiotic-resistant superbugs
How is the treatment applied?
The portable iontophoresis equipment is initially applied and calibrated to the patient during a clinic session. The equipment includes silver-nylon cloth electrodes attached to the body with medical tape, and a portable, palm-size electro-stimulator. The equipment is then taken home by the patient for continuous use over a number of days or even weeks, depending on the severity of the infection. Alternatively, a series of treatment sessions in the clinic can be arranged.
Background to the treatment system
Bacterial and Viral Infections: Silver Iontophoresis Treatment is non-invasive, and essentially similar to the patented antimicrobial system developed by the electromedical pioneer, American Orthopedist, Robert O Becker, and his team.
The background medical science behind this treatment system is not new. There are extensive medical-scientific journal articles on the effectiveness and mechanisms of action of electrically produced silver ions as powerful antibacterial and antiviral agents, including by the USA military. A sample of this medical literature is listed below.
Becker RO, Spadaro JA. Treatment of orthopaedic infections with electrically generated silver ions. A preliminary report. J Bone Joint Surg Am. 1978 Oct;60(7):871-81.
Nand S, Sengar GK, Nand S, Jain VK, Gupta TD. Dual use of silver for management of chronic bone infections and infected non-unions. J Indian Med Assoc. 1996 Mar;94(3):91-5.
Webster DA, Spadaro JA, Becker RO, Kramer S. Silver anode treatment of chronic osteomyelitis. Clin Orthop Relat Res. 1981 Nov-Dec;(161):105-14.
Becker RO, Flick AB, Becker AJ. Iontopheretic system for stimulation of tissue healing and regeneration. US 5814094 A. Sep 29, 1998.
Chu CS, McManus AT, Pruitt BA Jr, Mason AD Jr. Therapeutic effects of silver nylon dressings with weak direct current on Pseudomonas aeruginosa-infected burn wounds. J Trauma. 1988 Oct;28(10):1488-92.
Satyanand, Saxena AK, Agarwal A. Silver iontophoresis in chronic osteomyelitis. J Indian Med Assoc. 1986 May;84(5):134-6.
Uezono H. Effect of weak direct current with silver electrodes on bacterial growth. Nihon Seikeigeka Gakkai Zasshi. 1990 Sep;64(9):860-7. Department of Orthopaedic Surgery, Faculty of Medicine, Kagoshima University, Japan.
Raad I, Hachem R, Zermeno A, Stephens LC, Bodey GP. Silver iontophoretic catheter: a prototype of a long-term antiinfective vascular access device. J Infect Dis. 1996 Feb;173(2):495-8.
Low Voltage Iontophoresis
Chizmadzhev YA, Indenbom AV, Kuzmin PI, Galichenko SV, Weaver JC, Potts RO. Electrical properties of skin at moderate voltages: contribution of appendageal macropores. Biophys J. 1998 Feb;74(2 Pt 1):843-56.
Kasting GB, Bowman LA. DC electrical properties of frozen, excised human skin. Pharm Res. 1990 Feb;7(2):134-43.
Silver-Nylon Cloth – Effective Antibacterial Agent Release Medical Device
Deitch EA, Marino AA, Malakanok V, Albright JA. Silver nylon cloth: in vitro and in vivo evaluation of antimicrobial activity. J Trauma. 1987 Mar;27(3):301-4.
Deitch EA, Marino AA, Gillespie TE, Albright JA. Silver-nylon: a new antimicrobial agent. Antimicrob Agents Chemother. 1983 Mar;23(3):356-9.
P C MacKeen, S Person, S C Warner, W Snipes, S E Stevens, Jr. Silver-coated nylon fiber as an antibacterial agent. Antimicrob Agents Chemother. Jan 1987; 31(1): 93–99.
Barillo DJ, Pozza M, Margaret-Brandt M. A literature review of the military uses of silver-nylon dressings with emphasis on wartime operations. Burns. 2014 Dec;40 Suppl 1:S24-9.
Abboud EC, Settle JC, Legare TB, Marcet JE, Barillo D3, Sanchez JE. Silver-based dressings for the reduction of surgical site infection: review of current experience and recommendation for future studies. Burns. 2014 Dec;40 Suppl 1:S30-9.
Krieger BR, Davis DM, Sanchez JE, Mateka JJ, Nfonsam VN, Frattini JC, Marcet JE. The use of silver nylon in preventing surgical site infections following colon and rectal surgery. Dis Colon Rectum. 2011 Aug;54(8):1014-9.
Silver Ions and Nanoparticles – Broad Spectrum Antibacterial agents
Spadaro JA, Berger TJ, Barranco SD, Chapin SE, Becker RO. Antibacterial Effects of Silver Electrodes with Weak Direct Current. Antimicrobial Agents and Chemotherapy 1974;6(5):637-642.
Berger TJ, Spadaro JA, Chapin SE, Becker RO. Electrically Generated Silver Ions: Quantitative Effects on Bacterial and Mammalian Cells. Antimicrobial Agents and Chemotherapy 1976;9(2):357-358.
Morones-Ramirez JR, Winkler JA, Spina CS, Collins JJ. Silver Enhances Antibiotic Activity Against Gram-negative Bacteria. Science translational medicine 2013;5(190):190ra81.
Liau SY, Read DC, Pugh WJ, Furr JR, Russell AD. Interaction of silver nitrate with readily identifiable groups: relationship to the antibacterial action of silver ions. Lett Appl Microbiol. 1997 Oct;25(4):279-83.
Becker RO. Silver ions in the treatment of local infections. Met Based Drugs. 1999;6(4-5):311-4.
Xiu ZM, Zhang QB, Puppala HL, Colvin VL, Alvarez PJ. Negligible particle-specific antibacterial activity of silver nanoparticles. Nano Lett. 2012 Aug 8;12(8):4271-5.
Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M. Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects. Appl Microbiol Biotechnol. 2014 Mar;98(5):1951-61.
Silver Ions and Nanoparticles – Broad Spectrum Antivirals
Chen N, Zheng Y, Yin J, Li X, Zheng C. Inhibitory effects of silver nanoparticles against adenovirus type 3 in vitro. J Virol Methods. 2013 Nov;193(2):470-7.
Lara HH, Ayala-Nuñez NV, Ixtepan-Turrent L, Rodriguez-Padilla C. Mode of antiviral action of silver nanoparticles against HIV-1. Journal of Nanobiotechnology 2010;8:1.
Gaikwad S, Ingle A, Gade A, et al. Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3. International Journal of Nanomedicine 2013;8:4303-4314.
Elechiguerra JL, Burt JL, Morones JR, Camacho-Bragado A, Gao X, Lara HH, Yacaman MJ. Interaction of silver nanoparticles with HIV-1. J Nanobiotechnology. 2005 Jun 29;3:6.